Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720749 | 0.86 | SRD5A1 (0.58) | GRM5SRD5A1ESR2SRD5A2NR1H2 | |
| SCHEMBL18992022 | 0.86 | OGA (0.45) | GRM5SRD5A1ESR2SRD5A2NR1H2 | |
| SCHEMBL14720896 | 0.86 | GRM5 (0.46) | GRM5ESR2NR1H2MEN1KMT2A | |
| SCHEMBL1870570 | 0.83 | NR1H2 (0.54) | GRM5ESR2NR1H2MEN1KMT2A | |
| SCHEMBL4635083 | 0.83 | GRM5 (0.46) | GRM5ESR2NR1H2MEN1KMT2A | |
| SCHEMBL5497099 | 0.83 | MEN1 (0.55) | GRM5ESR2NR1H2MEN1KMT2A | |
| SCHEMBL1473227 | 0.83 | GPR119 (0.51) | GRM5SRD5A1ESR2SRD5A2NR1H2 | |
| SCHEMBL15699606 | 0.82 | ALDH1A1 (0.54) | GRM5OGASMN1; SMN2GPR119HTT | |
| SCHEMBL20304919 | 0.82 | SRD5A2 (0.55) | GRM5ESR2SRD5A2NR1H2MEN1 | |
| SCHEMBL16113569 | 0.81 | MAPT (0.54) | GRM5ESR2SRD5A2NR1H2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |