Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.55 |
| ▸ | L3MBTL3 | Q96JM7 | 9/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.55 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.49 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.49 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720751 | 0.83 | HRH3 (0.52) | HRH3L3MBTL1 | |
| SCHEMBL14720637 | 0.82 | L3MBTL3 (0.62) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL14723483 | 0.77 | L3MBTL3 (0.55) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL14721331 | 0.76 | HRH3 (0.45) | HRH3L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL14721173 | 0.76 | LRRK2 (0.54) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL14721333 | 0.76 | SRD5A2 (0.52) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL14720367 | 0.76 | HRH3 (0.42) | HRH3 | |
| SCHEMBL10138882 | 0.75 | HRH3 (0.64) | HRH3L3MBTL3L3MBTL1KCNH2 | |
| SCHEMBL3975118 | 0.72 | ALDH1A1 (0.65) | HRH3L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL523887 | 0.72 | HRH3 (0.68) | HRH3L3MBTL3L3MBTL1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | claimed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |