Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722282 | 0.87 | PER2 (0.36) | SRD5A2KCNH2ALDH1A1 | |
| SCHEMBL14721350 | 0.75 | HPGD (0.39) | SRD5A2SRD5A1OGA | |
| SCHEMBL31110446 | 0.73 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL16874589 | 0.73 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL16874593 | 0.73 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL14720708 | 0.72 | SRD5A1 (0.35) | SRD5A2SRD5A1OGA | |
| SCHEMBL14720825 | 0.72 | TP53 (0.46) | SRD5A2ALDH1A1 | |
| SCHEMBL16874684 | 0.72 | ERCC1 (0.48) | ALDH1A1 | |
| SCHEMBL16874683 | 0.72 | ERCC1 (0.48) | ALDH1A1 | |
| SCHEMBL14720948 | 0.70 | SRD5A2 (0.39) | SRD5A2SRD5A1OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |