Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 14/20 | 0.49 |
| ▸ | HTR2C | P28335 | 13/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14731175 | 0.86 | HTR2A (0.66) | ALDH1A1KDM4EMEN1KMT2AHTR2A | |
| SCHEMBL23884770 | 0.82 | ALDH1A1 (0.51) | ALDH1A1KDM4EMEN1KMT2AHTR2A | |
| SCHEMBL25442192 | 0.82 | HTR2A (0.68) | ALDH1A1KDM4EMEN1KMT2AHTR2A | |
| SCHEMBL4808083 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1KMT2AHTR2A | |
| SCHEMBL4808088 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1KMT2AHTR2A | |
| SCHEMBL6034142 | 0.80 | HTR2A (0.76) | ALDH1A1HTR2AHTR2CL3MBTL1GAA | |
| SCHEMBL18112937 | 0.78 | MAPT (0.60) | ALDH1A1KDM4EMEN1KMT2AHTR2A | |
| SCHEMBL14720852 | 0.78 | USP2 (0.54) | ALDH1A1MEN1KMT2AHTR2AHTR2C | |
| SCHEMBL4803183 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HTR2AHTR2CL3MBTL1GAA | |
| SCHEMBL4803177 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HTR2AHTR2CL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |