Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 10/20 | 1.00 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | BRD1 | O95696 | 4/20 | 0.44 |
| ▸ | BRD4 | O60885 | 3/20 | 0.44 |
| ▸ | BRPF3 | Q9ULD4 | 3/20 | 0.44 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.44 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12992386 | 0.86 | BRPF1 (0.75) | BRPF1PRKCIBRD1BRD4BRPF3 | |
| SCHEMBL20284352 | 0.81 | BRPF1 (0.68) | BRPF1PRKCITTRDAOKDM4E | |
| SCHEMBL22421744 | 0.80 | BRPF1 (0.67) | BRPF1PRKCIBRD4KDM4EALDH1A1 | |
| SCHEMBL22421717 | 0.79 | BRPF1 (0.66) | BRPF1PRKCIBRD4KDM4EALDH1A1 | |
| SCHEMBL11467250 | 0.79 | BRPF1 (0.65) | BRPF1BRD1BRD4BRPF3BRD9 | |
| SCHEMBL9250818 | 0.79 | BRPF1 (0.65) | BRPF1BRD1BRD4BRPF3BRD9 | |
| SCHEMBL31202639 | 0.79 | BRPF1 (0.65) | BRPF1BRD1BRD4BRPF3BRD9 | |
| SCHEMBL22421773 | 0.78 | BRPF1 (0.64) | BRPF1PRKCIBRD4KDM4EALDH1A1 | |
| SCHEMBL3481207 | 0.77 | BRPF1 (0.62) | BRPF1PRKCIKDM4EALDH1A1HPGD | |
| SCHEMBL31036167 | 0.77 | BRPF1 (0.62) | BRPF1PRKCIKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076470-A1 | SOX10 INHIBITORS AND USES THEREOF | THE GENERAL HOSPITAL CORPORATION (US) | 2025-04-10 | — | — | WO | disclosed |
| EP-3555063-B1 | 6-AMINO-QUINOLINONE COMPOUNDS AND DERIVATIVES AS BCL6 INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2020-09-16 | — | — | EP | disclosed |
| US-20170291875-A1 | QUINOLONES AS INHIBITORS OF CLASS IV BROMODOMAIN PROTEINS | UCL BUSINESS PLC (GB) | 2017-10-12 | — | — | US | disclosed |
| US-20170291875-A1 | QUINOLONES AS INHIBITORS OF CLASS IV BROMODOMAIN PROTEINS | UCL BUSINESS PLC (GB) | 2017-10-12 | — | — | US | disclosed |
| US-20170291875-A1 | QUINOLONES AS INHIBITORS OF CLASS IV BROMODOMAIN PROTEINS | UCL BUSINESS PLC (GB) | 2017-10-12 | — | — | US | disclosed |
| WO-2016034512-A1 | QUINOLONES AS INHIBITORS OF CLASS IV BROMODOMAIN PROTEINS | UCL BUSINESS PLC (GB) | 2016-03-10 | — | — | WO | disclosed |
| WO-2013027168-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS BROMODOMAIN INHIBITORS | PFIZER INC. (US) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170291875-A1 | QUINOLONES AS INHIBITORS OF CLASS IV BROMODOMAIN PROTEINS | BRD4, BRPF3, BRD3 | BRPF1 104/4885PRKCI 2074/4885BRD1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.