Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 2/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 3/20 | 0.63 |
| ▸ | CA2 | P00918 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23484773 | 1.00 | PLK1 (0.89) | PLK1SMN1; SMN2HPGDTSHRHTT | |
| SCHEMBL837307 | 0.94 | PLK1 (1.00) | PLK1SMN1; SMN2HPGDTSHRHTT | |
| Hydrochloric Acid SCHEMBL11037223 | 0.92 | PLK1 (0.96) | PLK1SMN1; SMN2HPGDTSHRHTT | |
| Phosphonic Acid SCHEMBL1060959 | 0.87 | PLK1 (0.85) | PLK1SMN1; SMN2HPGDTSHRHTT | |
| SCHEMBL16198923 | 0.85 | HDAC6 (0.70) | PLK1SMN1; SMN2HPGDTSHRHTT | |
| SCHEMBL14115137 | 0.85 | HDAC6 (0.70) | PLK1SMN1; SMN2HPGDTSHRHTT | |
| SCHEMBL8717056 | 0.84 | PLK1 (0.80) | PLK1SMN1; SMN2HTTCA1CA2 | |
| SCHEMBL23484625 | 0.83 | HPGD (0.63) | PLK1SMN1; SMN2HPGDTSHRHTT | |
| SCHEMBL7318116 | 0.83 | CA1 (0.89) | PLK1SMN1; SMN2HTTCA1CA2 | |
| SCHEMBL23484837 | 0.82 | PLK1 (0.59) | PLK1SMN1; SMN2HPGDTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028445-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | claimed |