Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 9/20 | 1.00 |
| ▸ | CYP11B2 | P19099 | 9/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | QPCT | Q16769 | 1/20 | 0.55 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.55 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265991 | 0.86 | CYP11B1 (0.75) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL21585708 | 0.82 | CYP11B1 (0.70) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL10940697 | 0.82 | CYP11B1 (0.70) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL11023652 | 0.82 | CYP11B1 (0.69) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL11107776 | 0.79 | CYP11B1 (0.65) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL11480633 | 0.78 | CYP11B1 (0.64) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL11019493 | 0.78 | CYP11B1 (0.63) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL14416068 | 0.77 | CYP11B1 (0.62) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL11085080 | 0.77 | CYP11B1 (0.62) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 | |
| SCHEMBL11019422 | 0.77 | CYP11B1 (0.61) | CYP11B1CYP11B2CYP19A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10167388-B2 | Block copolymers, synthesis and application as dehydrating and desalting of heavy crudes | INSTITUTO MEXICANO DEL PETROLEO (MX) | 2019-01-01 | — | — | US | disclosed |
| US-20170327686-A1 | BLOCK COPOLYMERS, SYNTHESIS AND APPLICATION AS DEHYDRATING AND DESALTING OF HEAVY CRUDES | MEXICANO INST PETROL (MX) | 2017-11-16 | — | — | US | disclosed |
| EP-2748168-A2 | INHIBITORS OF NEDD8-ACTIVATING ENZYME | Millennium Pharmaceuticals, Inc. (US) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013028832-A2 | INHIBITORS OF NEDD8-ACTIVATING ENZYME | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10167388-B2 | Block copolymers, synthesis and application as dehydrating and desalting of heavy crudes | DEGS1, AQP1, AQP3 | CYP11B1 1229/4885CYP11B2 1409/4885CYP19A1 1407/4885 |
| US-20170327686-A1 | BLOCK COPOLYMERS, SYNTHESIS AND APPLICATION AS DEHYDRATING AND DESALTING OF HEAVY CRUDES | DEGS1, AQP1, AQP3 | CYP11B1 1229/4885CYP11B2 1409/4885CYP19A1 1407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.