Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 10/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 9/20 | 0.43 |
| ▸ | TUBB | P07437 | 9/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 9/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 9/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 9/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 9/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 9/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 9/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 9/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 9/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 9/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 9/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 9/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 9/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14721923 | 0.86 | TUBB1 (0.40) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14722126 | 0.82 | NPSR1 (0.35) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14725441 | 0.79 | TUBB1 (0.45) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14725391 | 0.79 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL14725342 | 0.78 | TUBB1 (0.44) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14722455 | 0.78 | TUBB4A (0.44) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14725335 | 0.78 | TUBB4A (0.44) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14721811 | 0.77 | TUBB4A (0.48) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14722473 | 0.76 | TUBB4A (0.49) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14721855 | 0.76 | TUBB4A (0.49) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026942-A1 | TUBULIN BINDING AGENTS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2013-02-28 | — | — | WO | disclosed |