Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.31 |
| ▸ | TUBB | P07437 | 3/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722345 | 0.82 | KDM4E (0.35) | NPSR1POLBMAPTALDH1A1HPGD | |
| SCHEMBL14722156 | 0.82 | TUBB1 (0.43) | MAPK1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL14721923 | 0.82 | TUBB1 (0.40) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL14721961 | 0.79 | CYP19A1 (0.39) | ALDH1A1HPGDKDM4EMEN1MAPK1 | |
| SCHEMBL14721638 | 0.78 | TUBB4A (0.34) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL14723556 | 0.78 | TUBB4A (0.34) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL14725391 | 0.77 | SMN1; SMN2 (0.35) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL14723363 | 0.77 | TUBB4A (0.37) | NPSR1ATMKDM4EKMT2ATUBB4A | |
| SCHEMBL14722942 | 0.74 | ALDH1A1 (0.34) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL14722909 | 0.74 | TUBB4A (0.33) | MAPTALDH1A1HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026942-A1 | TUBULIN BINDING AGENTS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2013-02-28 | — | — | WO | disclosed |