SCHEMBL1472264

SCHEMBL1472264

CC(C)C(C)(C)[SiH2][O]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8599018 0.67
SCHEMBL5150467 0.64
SCHEMBL1150332 0.64
SCHEMBL9247209 0.64
SCHEMBL8632646 0.62
SCHEMBL10560645 0.62
SCHEMBL4580357 0.60
SCHEMBL7572902 0.60
SCHEMBL22974 0.59
SCHEMBL270228 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6861537-B2 Tricyclic and tetracyclic taxane intermediates FLORIDA STATE UNIVERSITY (US) 2005-03-01 US claimed
EP-0759929-B1 OXIDATION OF STEROIDS HAVING ALLYLIC GROUPS MERCK & CO INC (US) 2000-08-23 EP claimed
US-6005120-A INTERMEDIATE FOR USE IN THE PREPARATION OF TAXOL OR OTHER TRICYCLIC OR TETRACYCLIC TAXANES FLORIDA STATE UNIVERSITY (US) 1999-12-21 US claimed
EP-0198829-B1 9-HALOGEN-PROSTAGLANDINE DERIVATIVES, PREPARATION PROCESS AND UTILIZATION THEREOF AS DRUGS SCHERING AKTIENGESELLSCHAFT (DE) 1990-04-18 EP claimed
US-4886788-A Cyclodextrin clathrates of carbacyclin derivatives and their use as medicinal agents SCHERING AKTIENGESELLSCHAFT (DE) 1989-12-12 US claimed
EP-0009892-B1 CYCLOPENTENONE AND CYCLOPENTENOL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1983-04-13 EP claimed
US-4367340-A 4-Oxy-cyclopent-2-en-1-one derivative, a prostaglandin intermediate, and the process for its preparation THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1983-01-04 US claimed
US-4277403-A Prostaglandin intermediates PFIZER INC. (US) 1981-07-07 US claimed
US-4213907-A Prostaglandin intermediates PFIZER INC. (US) 1980-07-22 US claimed
EP-0002590-A1 Novel prostaglandin compounds, processes for the preparation thereof and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1979-06-27 EP claimed
US-4091207-A Prostaglandin intermediate including oxathio heterocyclic ring PFIZER INC. (US) 1978-05-23 US claimed
EP-2144974-B1 ORGANIC ELECTROLUMINESCENT DEVICE UDC IRELAND LTD (IE) 2018-06-13 EP disclosed
US-9472769-B2 Organic electroluminescent device UDC IRELAND LIMITED (IE) 2016-10-18 US disclosed
EP-2438989-B1 USE OF ASYMMETRIC HYDROGENATION CATALYST TAKASAGO PERFUMERY CO LTD (JP) 2016-04-13 EP disclosed
EP-2031037-B1 Organic electroluminescence device UDC IRELAND LTD (IE) 2015-12-09 EP disclosed
US-4091207-A Prostaglandin intermediate including oxathio heterocyclic ring PFIZER INC. (US) 1978-05-23 US disclosed
US-4059576-A CARDIOVASCULAR, OXYTOCICS HOFFMANN-LA ROCHE, INC. (US) 1977-11-22 US disclosed
US-4052446-A OXYTOCICS, CARDIOVASCULAR AGENTS HOFFMANN-LA ROCHE INC. (US) 1977-10-04 US disclosed
US-4052421-A 13-ETHINYL-STEROIDS AND PROCESSES FOR THEIR MANUFACTURE CIBA-GEIGY CORPORATION (US) 1977-10-04 US disclosed
US-4036871-A CARDIOVASCULAR AGENTS, LABOR INDUCERS, ABORTION HOFFMANN-LA ROCHE INC. (US) 1977-07-19 US disclosed