SCHEMBL14723019

SCHEMBL14723019

CC(C)(C)OC(=O)N(C1CC1)C1CCN(c2nn[nH]n2)CC1

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14722248 0.75 GPR119 (0.38) GPR119
SCHEMBL21626611 0.72 GPR119 (0.40) GPR119
SCHEMBL14723557 0.71 GPR119 (0.39) GPR119
SCHEMBL16580729 0.70 GPR119 (0.50) GPR119
SCHEMBL31211025 0.69 PDE10A (0.42) GPR119
SCHEMBL25105974 0.69 KMT2A (0.49) GPR119
SCHEMBL30228730 0.69 KMT2A (0.49) GPR119
SCHEMBL25105323 0.69 KMT2A (0.49) GPR119
SCHEMBL30229290 0.69 AAK1 (0.40) GPR119
SCHEMBL30229028 0.69 KMT2A (0.49) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013026587-A1 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS PROSIDION LIMITED (GB) 2013-02-28 WO disclosed
WO-2013026587-A1 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS PROSIDION LIMITED (GB) 2013-02-28 WO disclosed