SCHEMBL14723248

SCHEMBL14723248

FC(F)(F)C(F)(F)CCn1cncn1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EGLN3 Q9H6Z9 2/20 0.44
CYP19A1 P11511 2/20 0.40
FDPS P14324 1/20 0.37
KDM4E B2RXH2 4/20 0.37
ALOX15 P16050 1/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
POLB P06746 1/20 0.37
HTT P42858 1/20 0.37
MAPK1 P28482 1/20 0.36
HSP90AA1 P07900 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
LMNA P02545 2/20 0.34
TP53 P04637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3371124 0.76 EGLN3 (0.44) EGLN3CYP19A1FDPSKDM4EALDH1A1
SCHEMBL10721461 0.75 EGLN3 (0.47) EGLN3CYP19A1FDPSKDM4EALDH1A1
SCHEMBL2679933 0.71
SCHEMBL10338984 0.71 EGLN3 (0.56) EGLN3CYP19A1KDM4EALDH1A1MAPT
SCHEMBL17159811 0.71 EGLN3 (0.56) EGLN3CYP19A1KDM4EALOX15ALDH1A1
SCHEMBL1485386 0.70 FDPS (0.50) EGLN3CYP19A1FDPSKDM4EALOX15
SCHEMBL1289831 0.69
SCHEMBL29518112 0.69 EGLN3 (0.54) EGLN3CYP19A1KDM4EALOX15ALDH1A1
SCHEMBL2535061 0.69 EGLN3 (0.54) EGLN3CYP19A1KDM4EALOX15ALDH1A1
SCHEMBL28667189 0.68 LMNA (0.37) FDPSMAPTPOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9390864-B2 Additives for dye-sensitized solar cells MERCK PATENT GMBH (DE) 2016-07-12 US disclosed
US-20150340165-A1 ADDITIVES FOR DYE-SENSITIZED SOLAR CELLS MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-9159499-B2 Additives for dye-sensitized solar cells MERCK PATENT GMBH (DE) 2015-10-13 US disclosed
EP-2820105-A1 ADDITIVES FOR DYE-SENSITIZED SOLAR CELLS Merck Patent GmbH (DE) 2015-01-07 EP disclosed
US-20140190567-A1 ADDITIVES FOR DYE-SENSITIZED SOLAR CELLS MERCK PATENT GMBH (DE) 2014-07-10 US disclosed
WO-2013026563-A1 ADDITIVES FOR DYE-SENSITIZED SOLAR CELLS MERCK PATENT GMBH (DE) 2013-02-28 WO disclosed