SCHEMBL14723490

SCHEMBL14723490

C=CCOC(=O)/C=C\C(=O)O.C=COC(C)=O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
CACNA1B Q00975 1/20 0.47
APBA1 Q02410 1/20 0.47
HCAR2 Q8TDS4 12/20 0.47
APP P05067 1/20 0.37
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 2/20 0.32
CYP2C9 P11712 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2358642 1.00 MAPT (0.47) MAPTCACNA1BAPBA1HCAR2APP
SCHEMBL2358640 1.00 MAPT (0.47) MAPTCACNA1BAPBA1HCAR2APP
SCHEMBL28110751 0.93 MAPT (0.53) MAPTCACNA1BAPBA1HCAR2APP
SCHEMBL10607753 0.88 MAPT (0.38) MAPTCACNA1BAPBA1HCAR2APP
Acetic Acid SCHEMBL4769574 0.88 HCAR2 (0.55) MAPTCACNA1BAPBA1HCAR2APP
SCHEMBL11884935 0.87 MAPT (0.37) MAPTCACNA1BAPBA1HCAR2APP
SCHEMBL39644 0.86 MAPT (0.60) MAPTCACNA1BAPBA1HCAR2APP
SCHEMBL29985915 0.86 MAPT (0.60) MAPTCACNA1BAPBA1HCAR2APP
SCHEMBL254252 0.86 MAPT (0.60) MAPTCACNA1BAPBA1HCAR2APP
SCHEMBL39643 0.86 MAPT (0.60) MAPTCACNA1BAPBA1HCAR2APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103562239-B Comb polymers as dispersants for alkali-activated binders SIKA技术股份公司 2016-06-22 CN disclosed
US-9365454-B2 Comb polymers as dispersants for alkaline activated binders SIKA TECHNOLOGY AG (CH) 2016-06-14 US disclosed
EP-2744878-A1 FUEL PELLETS AND BRIQUETTES, THEIR PRODUCTION AND USE Celanese Emulsions GmbH (DE) 2014-06-25 EP disclosed
US-20140080943-A1 COMB POLYMERS AS DISPERSANTS FOR ALKALINE ACTIVATED BINDERS SIKA TECHNOLOGY AG (CH) 2014-03-20 US disclosed
CN-101163523-B Tooth whitening compositions containing cross-linked polymer-peroxide COLGATE PALMOLIVE CO 2013-06-19 CN disclosed
WO-2013027082-A1 FUEL PELLETS AND BRIQUETTES, THEIR PRODUCTION AND USE CELANESE EMULSIONS GMBH (DE) 2013-02-28 WO disclosed
CN-101163523-A Tooth whitening compositions containing cross-linked polymer-peroxide COLGATE PALMOLIVE CO (US) 2008-04-16 CN disclosed