SCHEMBL2358640

SCHEMBL2358640

C=CCOC(=O)/C=C/C(=O)O.C=COC(C)=O

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.47
CACNA1B Q00975 1/20 0.47
APBA1 Q02410 1/20 0.47
HCAR2 Q8TDS4 12/20 0.47
APP P05067 1/20 0.37
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 2/20 0.32
CYP2C9 P11712 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14723490 1.00 MAPT (0.47) MAPTCACNA1BAPBA1HCAR2APP
SCHEMBL2358642 1.00 MAPT (0.47) MAPTCACNA1BAPBA1HCAR2APP
SCHEMBL28110751 0.93 MAPT (0.53) MAPTCACNA1BAPBA1HCAR2APP
SCHEMBL10607753 0.88 MAPT (0.38) MAPTCACNA1BAPBA1HCAR2APP
Acetic Acid SCHEMBL4769574 0.88 HCAR2 (0.55) MAPTCACNA1BAPBA1HCAR2APP
SCHEMBL11884935 0.87 MAPT (0.37) MAPTCACNA1BAPBA1HCAR2APP
SCHEMBL39644 0.86 MAPT (0.60) MAPTCACNA1BAPBA1HCAR2APP
SCHEMBL29985915 0.86 MAPT (0.60) MAPTCACNA1BAPBA1HCAR2APP
SCHEMBL254252 0.86 MAPT (0.60) MAPTCACNA1BAPBA1HCAR2APP
SCHEMBL39643 0.86 MAPT (0.60) MAPTCACNA1BAPBA1HCAR2APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110190438-A1 METHOD OF IMPROVING THE COLD FLOW PROPERTIES OF A PARAFFIN-CONTAINING FLUID SCHLUMBERGER NORGE AS (NO) 2011-08-04 US claimed
WO-2010003892-A1 METHOD OF IMPROVING THE COLD FLOW PROPERTIES OF A PARAFFIN-CONTAINING FLUID M-I SWACO NORGE AS (NO) 2010-01-14 WO claimed
EP-4326840-A1 POLYMERIC POUR POINT DEPRESSANTS FOR WAXY CRUDE OILS Clariant International Ltd (CH) 2024-02-28 EP disclosed
CN-117222724-A Polymeric pour point depressants for waxy crude oils 科莱恩国际有限公司 2023-12-12 CN disclosed
US-11692053-B2 Polymeric pour point depressants for waxy crude oils CLARIANT INTERNATIONAL LTD (CH) 2023-07-04 US disclosed
US-11008523-B2 Chemical inhibitors with sub-micron materials as additives for enhanced flow assurance CAMERON INTERNATIONAL CORPORATION (US) 2021-05-18 US disclosed
WO-2019113265-A1 COMPOSITION OF A FLOW IMPROVER AND METHOD OF USING THE SAME IN HYDROCARBON FLUIDS M-I L.L.C. (US) 2019-06-13 WO disclosed
US-10316712-B2 Lubricant compositions for surface finishing of materials EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2019-06-11 US disclosed
EP-3389902-A1 LUBRICANT COMPOSITIONS FOR SURFACE FINISHING OF MATERIALS ExxonMobil Research and Engineering Company (US) 2018-10-24 EP disclosed
EP-2814921-B1 MIXTURES OF OLEFIN-ESTER COPOLYMER WITH POLYOLEFIN AS VISCOSITY MODIFIER LUBRIZOL CORP (US) 2017-11-08 EP disclosed
US-9758743-B2 Mixtures of olefin-ester copolymer with polyolefin as viscosity modifier THE LUBRIZOL CORPORATION (US) 2017-09-12 US disclosed
US-4062786-A Lactone oxazolines as oleaginous additives EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-12-13 US disclosed
US-4049564-A Oxazoline derivatives as additives useful in oleaginous compositions EXXON RESEARCH & ENGINEERING CO. (US) 1977-09-20 US disclosed
US-4042523-A Olefin-thionophosphine sulfide reaction products, their derivatives and use thereof as oil and fuel additives EXXON RESEARCH AND ENGINEERING CO. (US) 1977-08-16 US disclosed
US-4033889-A Terpolymer dispersant - VI improver SHELL OIL COMPANY (US) 1977-07-05 US disclosed
US-4033888-A Dispersant VI improver SHELL OIL COMPANY (US) 1977-07-05 US disclosed
US-4032700-A PROCESS FOR THE PREPARATION OF AMINATED POLYMERS USEFUL AS ADDITIVES FOR FUELS AND LUBRICANTS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-06-28 US disclosed
US-4000353-A Hydroxylated polymers useful as additives for fuels and lubricants EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-12-28 US disclosed
US-3937731-A OIL SOLUBLE ADDITIVES MINERAL LUBRICATING OILS EXXON RESEARCH & ENGINEERING CO. (US) 1976-02-10 US disclosed
US-3931024-A OIL ADDITIVE EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-01-06 US disclosed