Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 10/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.35 |
| ▸ | CTSB | P07858 | 9/20 | 0.33 |
| ▸ | CTSL | P07711 | 6/20 | 0.33 |
| ▸ | CTSS | P25774 | 5/20 | 0.33 |
| ▸ | CTSC | P53634 | 4/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 4/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11145232 | 0.75 | — | — | |
| SCHEMBL16015436 | 0.75 | DPP7 (0.44) | — | |
| SCHEMBL14730193 | 0.75 | JAK2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL28691974 | 0.72 | TLR7 (0.34) | — | |
| SCHEMBL12827029 | 0.71 | KDM4E (0.34) | IRAK4DPP4 | |
| SCHEMBL19020836 | 0.71 | KDM4E (0.39) | IRAK4DPP4 | |
| Hydrochloric Acid SCHEMBL29424737 | 0.70 | KDM4E (0.39) | — | |
| SCHEMBL28202703 | 0.70 | ALDH1A1 (0.44) | DPP4 | |
| SCHEMBL28202704 | 0.70 | TEAD1 (0.31) | — | |
| SCHEMBL3872945 | 0.70 | HRH3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |