Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.61 |
| ▸ | KDM1A | O60341 | 3/20 | 0.51 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14730265 | 1.00 | DPP4 (0.61) | DPP4KDM1AKDM1BDRD2DRD3 | |
| SCHEMBL14723600 | 1.00 | DPP4 (0.61) | DPP4KDM1AKDM1BDRD2DRD3 | |
| SCHEMBL470598 | 0.90 | DPP4 (0.61) | DPP4KDM1AKDM1BDRD2DRD3 | |
| SCHEMBL147328 | 0.86 | DPP4 (0.63) | DPP4KDM1ADRD2DRD3FUCA1 | |
| SCHEMBL147330 | 0.86 | DPP4 (0.63) | DPP4KDM1ADRD2DRD3FUCA1 | |
| SCHEMBL1725958 | 0.86 | DPP4 (0.63) | DPP4KDM1ADRD2DRD3FUCA1 | |
| SCHEMBL147329 | 0.86 | DPP4 (0.63) | DPP4KDM1ADRD2DRD3FUCA1 | |
| SCHEMBL14730218 | 0.86 | DPP4 (0.63) | DPP4KDM1AKDM1BDRD2DRD3 | |
| SCHEMBL6125565 | 0.86 | DPP4 (0.63) | DPP4KDM1AKDM1BDRD2DRD3 | |
| SCHEMBL149731 | 0.86 | DPP4 (0.64) | DPP4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |