Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL463330 | 1.00 | NPSR1 (0.43) | NPSR1HTTMEN1KMT2ACCR5 | |
| SCHEMBL14723617 | 1.00 | NPSR1 (0.43) | NPSR1HTTMEN1KMT2ACCR5 | |
| SCHEMBL14723613 | 1.00 | NPSR1 (0.43) | NPSR1HTTMEN1KMT2ACCR5 | |
| SCHEMBL611817 | 0.89 | DRD2 (0.51) | MEN1KMT2ACCR5DRD2DRD3 | |
| SCHEMBL1725311 | 0.89 | DRD2 (0.51) | MEN1KMT2ACCR5DRD2DRD3 | |
| SCHEMBL1725314 | 0.89 | DRD2 (0.51) | MEN1KMT2ACCR5DRD2DRD3 | |
| SCHEMBL611816 | 0.89 | DRD2 (0.51) | MEN1KMT2ACCR5DRD2DRD3 | |
| SCHEMBL611818 | 0.89 | DRD2 (0.51) | MEN1KMT2ACCR5DRD2DRD3 | |
| SCHEMBL14722768 | 0.87 | DPP4 (0.41) | HTTMEN1KMT2ACCR5DRD2 | |
| SCHEMBL459874 | 0.87 | DPP4 (0.41) | HTTMEN1KMT2ACCR5DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |