Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14723651 | 0.87 | SLC40A1 (0.41) | SLC40A1CYP2C9PTGER1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12790198 | 0.84 | HTT (0.41) | MAPK14ALDH1A1SMN1; SMN2HPGDHTT | |
| SCHEMBL13667124 | 0.84 | METAP1 (0.41) | MAPK14ALDH1A1SMN1; SMN2HPGDHTT | |
| SCHEMBL13667088 | 0.80 | KDM4E (0.39) | HDAC1CYP2C9ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL12847501 | 0.80 | MAPT (0.39) | ALDH1A1SMN1; SMN2HPGDHTTHSD17B10 | |
| SCHEMBL12847422 | 0.77 | SRC (0.41) | MAPK14KDM4EBRAFAURKAMETAP1 | |
| SCHEMBL2936138 | 0.76 | BRAF (0.43) | MAPK14BRAFAURKAAAK1SRC | |
| SCHEMBL13666962 | 0.74 | MAPT (0.35) | ALDH1A1SMN1; SMN2HPGDHTTHSD17B10 | |
| SCHEMBL6279532 | 0.73 | BRD4 (0.48) | SLC40A1HDAC1CYP2C9PTGER1MEN1 | |
| SCHEMBL12847306 | 0.73 | MAPT (0.43) | MAPK14KDM4EBRAFMETAP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383816-B2 | Aryl-quinolyl compounds and their use | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2013-02-26 | — | — | US | disclosed |