Ethylenediamine

Ethylenediamine

SCHEMBL1472377

NCCN.O=C(O)C(CO)(CO)c1ccccc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
TSHR P16473 1/20 0.52
HTT P42858 1/20 0.44
KIF11 P52732 10/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
HIF1A Q16665 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP2C19 P33261 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10762081 0.92 ALDH1A1 (0.59) ALDH1A1TSHRHTTKIF11CYP1A2
SCHEMBL27473190 0.88 ALDH1A1 (0.52) ALDH1A1TSHRHTTKIF11CYP1A2
SCHEMBL6916102 0.80 ALDH1A1 (0.52) ALDH1A1TSHRHTTKIF11CYP1A2
SCHEMBL6761465 0.80 ALDH1A1 (0.52) ALDH1A1TSHRHTTKIF11CYP1A2
SCHEMBL28952197 0.78 HTT (0.56) ALDH1A1TSHRHTTKIF11CYP1A2
SCHEMBL1233226 0.78 TSHR (0.50) ALDH1A1TSHRHTTKIF11CYP1A2
SCHEMBL6761557 0.77 TSHR (0.49) ALDH1A1TSHRHTTKIF11CYP1A2
SCHEMBL8607678 0.76 ALDH1A1 (0.51) ALDH1A1TSHRHTTKIF11CYP1A2
SCHEMBL8607670 0.76 ALDH1A1 (0.51) ALDH1A1TSHRHTTKIF11CYP1A2
SCHEMBL6758856 0.76 ALDH1A1 (0.47) ALDH1A1TSHRHTTKIF11CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8294282-B2 Semiconductor device and adhesive sheet KABUSHIKI KAISHA TOSHIBA (JP) 2012-10-23 US disclosed
US-20110068480-A1 SEMICONDUCTOR DEVICE AND ADHESIVE SHEET TOSHIBA MEMORY CORPORATION (JP) 2011-03-24 US disclosed
US-20040142835-A1 Washing liquid for semiconductor substrate SUMITOMO CHEMICAL COMPANY, LIMITED 2004-07-22 US disclosed
US-6498132-B2 SURFACE TREATMENT COMPOSITION COMPRISES A COMPLEXING AGENT AS A METAL DEPOSITION PREVENTIVE COMPRISING ATLEAST ONE AROMATIC HYDROCARBON RING CONTAINING HYDROXY OR O-GROUP DIRECTLY ATTACHED WITH RING CARBON AND A SECOND COMPLEXING AGENT MITSUBISHI CHEMICAL CORPORATION (JP) 2002-12-24 US disclosed
US-20020045556-A1 Method for treating surface of substrate and surface treatment composition used for the same MITSUBISHI CHEMICAL CORPORATION (JP) 2002-04-18 US disclosed
US-5885362-A APPLYING TO SURFACE A COMPOSITION COMPRISING A LIQUID MEDIUM AND AT LEAST ONE COMPLEXING AGENT, FOR EXAMPLE ETHYLENEDIAMINEDIORTHOHYDROXYPHENYLACETIC ACID MITSUBISHI CHEMICAL CORPORATION (JP) 1999-03-23 US disclosed
EP-0852462-A1 PRODUCTS AND PROCESSES FOR THE SUSTAINED RELEASE OF AGRICULTURAL ACTIVE INGREDIENTS Ciba Specialty Chemicals Water Treatments Limited (GB) 1998-07-15 EP disclosed
EP-0789071-A1 METHOD FOR TREATING SURFACE OF SUBSTRATE AND SURFACE TREATMENT COMPOSITION THEREFOR MITSUBISHI CHEMICAL CORPORATION (JP) 1997-08-13 EP disclosed
WO-1997007675-A1 PRODUCTS AND PROCESSES FOR THE SUSTAINED RELEASE OF AGRICULTURAL ACTIVE INGREDIENTS ALLIED COLLOIDS LIMITED (GB) 1997-03-06 WO disclosed