SCHEMBL28952197

SCHEMBL28952197

NCC(CO)(C(N)=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.56
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47
KCNN4 O15554 6/20 0.42
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
TAAR1 Q96RJ0 1/20 0.41
KIF11 P52732 4/20 0.38
LMNA P02545 1/20 0.37
CHRM2 P08172 1/20 0.37
CYP2D6 P10635 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
KCNH2 Q12809 1/20 0.37
CYP2C19 P33261 1/20 0.37
HIF1A Q16665 1/20 0.37
CYP1A2 P05177 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27473190 0.86 ALDH1A1 (0.52) HTTMAPTKMT2AKCNN4ALDH1A1
SCHEMBL27927747 0.83 HTT (0.54) HTTMAPTKMT2AKCNN4ALDH1A1
Ethylenediamine SCHEMBL1472377 0.78 ALDH1A1 (0.52) HTTMAPTKMT2AALDH1A1TSHR
SCHEMBL16416822 0.78 HTT (0.49) HTTMAPTKMT2AKCNN4ALDH1A1
SCHEMBL10762081 0.77 ALDH1A1 (0.59) HTTMAPTKMT2AKCNN4ALDH1A1
SCHEMBL431187 0.76 HTT (0.59) HTTMAPTKMT2AKCNN4ALDH1A1
SCHEMBL25436346 0.74 HTT (0.45) HTTMAPTKMT2AKCNN4ALDH1A1
SCHEMBL28140828 0.74 MAPT (0.52) HTTMAPTKMT2AKCNN4TSHR
SCHEMBL3994296 0.74 MAPT (0.57) HTTMAPTKMT2AKCNN4TSHR
SCHEMBL11021099 0.74 MAPT (0.52) HTTMAPTKMT2AKCNN4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115368258-A Preparation process of amide compound 浙江工业大学 2022-11-22 CN disclosed