Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | MAPT | P10636 | 3/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.75 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.75 |
| ▸ | VDR | P11473 | 3/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.75 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.75 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | CDC25A | P30304 | 1/20 | 0.75 |
| ▸ | PGR | P06401 | 1/20 | 0.75 |
| ▸ | HPGD | P15428 | 1/20 | 0.75 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.75 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.75 |
| ▸ | DRD3 | P35462 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816850 | 0.89 | MAPT (0.78) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL30253080 | 0.89 | MAPT (0.78) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL11329349 | 0.88 | VDR (0.79) | MAPTVDRADORA3PGRABCB11 | |
| SCHEMBL11329344 | 0.88 | VDR (0.79) | MAPTVDRADORA3PGRABCB11 | |
| SCHEMBL4913184 | 0.88 | MEN1 (0.80) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL11225746 | 0.88 | MEN1 (0.80) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL3175941 | 0.88 | MEN1 (0.80) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL9361678 | 0.88 | MEN1 (0.80) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL7086287 | 0.88 | MEN1 (0.80) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL30692696 | 0.88 | MEN1 (0.80) | MEN1KMT2AMAPTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119241-A1 | Preparation of 24 alkyl analogs of cholecalciferol and non-racemic compounds | INSTYTUT FARMACEUTYCZNY (PL) | 2005-06-02 | — | — | US | claimed |
| EP-1497264-A2 | PREPARATION OF 24-ALKYL ANALOGS OF CHOLECALCIFEROL AND NON-RACEMIC COMPOUNDS | INSTYTUT FARMACEUTYCZNY (PL) | 2005-01-19 | — | — | EP | claimed |
| WO-2003087048-A2 | PREPARATION OF 24 ALKYL ANALOGS OF CHOLECALCIFEROL AND NON-RACEMIC COMPOUNDS | INSTYTUT FARMACEUTYCZNY (PL) | 2003-10-23 | — | — | WO | claimed |
| US-7915241-B2 | Reacting a sulfone intermediate, possessing a (5E) or (5Z) configuration with an aldehyde having an (R) or an (S) configuration in the presence of a strong base, in an aprotic solvent; synthetic analog of vitamin D3-calcipotriol, biologically active compound used in medical treatment | INSTYTUT FARMACEUTYCZNY (PL) | 2011-03-29 | — | — | US | disclosed |
| US-20050119241-A1 | Preparation of 24 alkyl analogs of cholecalciferol and non-racemic compounds | INSTYTUT FARMACEUTYCZNY (PL) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119241-A1 | Preparation of 24 alkyl analogs of cholecalciferol and non-racemic compounds | CYP24A1, CYP2R1, VDR | MEN1 2140/4885KMT2A 4779/4885MAPT 4879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.