Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19134543 | 0.81 | GRM5 (0.39) | ALDH1A1LMNAGRM5EPHX2 | |
| SCHEMBL14724231 | 0.77 | MEN1 (0.34) | ALDH1A1CNR1CNR2BRAF | |
| SCHEMBL84836 | 0.76 | MEN1 (0.44) | ALDH1A1LMNAGRM5 | |
| SCHEMBL9891486 | 0.76 | ALDH1A1 (0.35) | ALDH1A1CNR1CNR2BRAF | |
| SCHEMBL1013430 | 0.76 | BRAF (0.32) | CNR1CNR2BRAF | |
| SCHEMBL9892872 | 0.76 | BRAF (0.34) | EPHX2CNR1CNR2BRAF | |
| SCHEMBL19134534 | 0.74 | ALDH1A1 (0.38) | ALDH1A1LMNAGRM5EPHX2 | |
| SCHEMBL9891816 | 0.73 | EGFR (0.46) | EPHX2CNR1CNR2BRAF | |
| SCHEMBL15469304 | 0.73 | ALDH1A1 (0.40) | ALDH1A1LMNAGRM5 | |
| SCHEMBL14723926 | 0.71 | CNR1 (0.41) | ALDH1A1CNR1CNR2BRAFCCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383615-B2 | Azetidine 2-carboxamide derivatives which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-26 | — | — | US | disclosed |