SCHEMBL14724014

SCHEMBL14724014

Cc1ccc(N(c2ccc(-c3ccccc3)cc2)c2ccc(C)cc2C)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
LMNA P02545 3/20 0.40
HTT P42858 1/20 0.40
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
MAPT P10636 2/20 0.38
KDM4E B2RXH2 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
HPRT1 P00492 1/20 0.37
NPC1 O15118 4/20 0.37
GAA P10253 2/20 0.37
CYP2C19 P33261 1/20 0.37
POLB P06746 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15946725 0.98 SMN1; SMN2 (0.41) RAB9ASMN1; SMN2LMNAHTTMEN1
SCHEMBL14423299 0.98 SMN1; SMN2 (0.41) RAB9ASMN1; SMN2LMNAHTTMEN1
SCHEMBL12388883 0.95 SMN1; SMN2 (0.38) RAB9ASMN1; SMN2LMNAHTTMEN1
SCHEMBL13929906 0.95 ALDH1A1 (0.37) RAB9ASMN1; SMN2LMNAHTTMEN1
SCHEMBL12388890 0.95 SMN1; SMN2 (0.39) RAB9ASMN1; SMN2LMNAHTTMEN1
SCHEMBL2846530 0.95 SMN1; SMN2 (0.38) RAB9ASMN1; SMN2LMNAHTTMEN1
SCHEMBL13929895 0.95 SMN1; SMN2 (0.38) RAB9ASMN1; SMN2LMNAHTTMEN1
SCHEMBL19826255 0.93 MEN1 (0.38) RAB9ASMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL12533878 0.93 MEN1 (0.38) RAB9ASMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL7613942 0.93 MEN1 (0.38) RAB9ASMN1; SMN2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170329199-A1 ELECTROCHROMIC DEVICE RICOH COMPANY, LTD. (JP) 2017-11-16 US disclosed
US-20170235203-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT RICOH COMPANY, LTD. (JP) 2017-08-17 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-8383305-B2 Image forming apparatus RICOH COMPANY, LTD. (JP) 2013-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170235203-A1 ELECTROCHROMIC ELEMENT AND ELECTROCHROMIC DIMMING ELEMENT TET2, TET1, TET3 RAB9A 4195/4885SMN1; SMN2 3945/4885LMNA 1998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.