SCHEMBL2846530

SCHEMBL2846530

Cc1ccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4ccc(C)cc4C)cc3)cc2)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.38
LMNA P02545 3/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38
APP P05067 1/20 0.36
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 3/20 0.35
CYP2C19 P33261 2/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
GAA P10253 2/20 0.34
ALOX12 P18054 1/20 0.34
TP53 P04637 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13929895 1.00 SMN1; SMN2 (0.38) SMN1; SMN2LMNAHTTRAB9AAPP
SCHEMBL13929906 0.97 ALDH1A1 (0.37) SMN1; SMN2LMNAHTTRAB9AAPP
SCHEMBL15946725 0.96 SMN1; SMN2 (0.41) SMN1; SMN2LMNAHTTRAB9AALDH1A1
SCHEMBL14423299 0.96 SMN1; SMN2 (0.41) SMN1; SMN2LMNAHTTRAB9AALDH1A1
SCHEMBL14047730 0.95 SMN1; SMN2 (0.35) SMN1; SMN2LMNAHTTRAB9AAPP
SCHEMBL14724014 0.95 RAB9A (0.40) SMN1; SMN2LMNAHTTRAB9AALDH1A1
SCHEMBL19270237 0.95 ALDH1A1 (0.38) SMN1; SMN2LMNAHTTRAB9AAPP
SCHEMBL19270230 0.94 TDP1 (0.39) SMN1; SMN2LMNAHTTRAB9AAPP
SCHEMBL12388884 0.94 SMN1; SMN2 (0.38) SMN1; SMN2LMNAHTTRAB9AAPP
SCHEMBL12388890 0.93 SMN1; SMN2 (0.39) SMN1; SMN2LMNAHTTRAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5192633-A Ionization potential MITA INDUSTRIAL CO., LTD. (JP) 1993-03-09 US claimed
WO-2024122192-A1 IMAGE FORMING DEVICE AND PROCESS CARTRIDGE キヤノン株式会社 2024-06-13 WO disclosed
US-11782353-B2 Method for producing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2023-10-10 US disclosed
US-11782353-B2 Method for producing electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 2023-10-10 US disclosed
US-20230288827-A1 PHOTOSENSITIVE BODY INCLUDING PROTECTIVE LAYER HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2023-09-14 US disclosed
US-20230273535-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-31 US disclosed
US-20230273535-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-31 US disclosed
WO-2023075748-A1 PHOTOCONDUCTOR DRUM HAVING A LAYER HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2023-05-04 WO disclosed
EP-4170431-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS Canon Kabushiki Kaisha (JP) 2023-04-26 EP disclosed
US-20230124743-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2023-04-20 US disclosed
EP-0614131-A2 Image forming apparatus MITA INDUSTRIAL CO., LTD. (JP) 1994-09-07 EP disclosed
EP-0613067-A2 Transfer in an image-forming apparatus MITA INDUSTRIAL CO. LTD. (JP) 1994-08-31 EP disclosed
EP-0397146-B1 Laminate type photosensitive material for electrophotography MITA INDUSTRIAL CO LTD (JP) 1994-08-03 EP disclosed
US-5328789-A Copies or laser printing MITA INDUSTRIAL CO., LTD. (JP) 1994-07-12 US disclosed
US-5324610-A Improved sensitivity, residual potential MITA INDUSTRIAL CO., LTD. (JP) 1994-06-28 US disclosed
EP-0599526-A1 An electrophotographic photoconductor MITA INDUSTRIAL CO., LTD. (JP) 1994-06-01 EP disclosed
EP-0591010-A1 Organic photosensitive material for electrophotography MITA INDUSTRIAL CO., LTD. (JP) 1994-04-06 EP disclosed
EP-0574154-A1 An electrophotographic organic photoconductor MITA INDUSTRIAL CO., LTD. (JP) 1993-12-15 EP disclosed
EP-0506387-A2 Electrophotographic organic photosensitive material MITA INDUSTRIAL CO., LTD. (JP) 1992-09-30 EP disclosed
EP-0397146-A2 Laminate type photosensitive material for electrophotography MITA INDUSTRIAL CO., LTD. (JP) 1990-11-14 EP disclosed