Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14723936 | 0.83 | EGFR (0.41) | EGFRALDH1A1GAAMAPTKMT2A | |
| SCHEMBL4102589 | 0.78 | EGFR (0.74) | EGFRMAPTKMT2APOLBPKM | |
| SCHEMBL4110225 | 0.75 | ALDH1A1 (0.72) | EGFRALDH1A1GAAMAPTKMT2A | |
| SCHEMBL9893113 | 0.74 | EGFR (0.56) | EGFRALDH1A1GAAMAPTKMT2A | |
| SCHEMBL9892904 | 0.74 | MAPK14 (0.54) | EGFRALDH1A1GAAKMT2APOLB | |
| SCHEMBL11966193 | 0.74 | RAF1 (0.43) | ALDH1A1GAAMAPTKMT2APOLB | |
| SCHEMBL26789821 | 0.73 | EGFR (0.55) | EGFRALDH1A1GAAMAPTKMT2A | |
| SCHEMBL2527939 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MAPTPOLB | |
| SCHEMBL24429344 | 0.71 | HDAC6 (0.49) | ALDH1A1 | |
| SCHEMBL9892787 | 0.71 | EGFR (0.52) | EGFRALDH1A1GAAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383615-B2 | Azetidine 2-carboxamide derivatives which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-26 | — | — | US | disclosed |