Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14724235 | 0.83 | EGFR (0.47) | EGFRADORA1ALDH1A1GAAMAPT | |
| SCHEMBL11966193 | 0.75 | RAF1 (0.43) | ALDH1A1GAAMAPTNPC1RAB9A | |
| SCHEMBL9891521 | 0.75 | EGFR (0.64) | EGFRKDRCNR2HPGDCNR1 | |
| SCHEMBL9891519 | 0.73 | MAPK14 (0.55) | L3MBTL1ALDH1A1GAACNR2CNR1 | |
| SCHEMBL12155319 | 0.73 | EGFR (0.50) | EGFRKDRCNR2HPGDCNR1 | |
| SCHEMBL2527939 | 0.73 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTNPC1RAB9A | |
| SCHEMBL24429344 | 0.72 | HDAC6 (0.49) | ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL9416864 | 0.72 | CNR1 (0.52) | EGFRKDRCNR2HPGDCNR1 | |
| SCHEMBL2797765 | 0.71 | IGF1R (0.39) | KDRALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL2529954 | 0.71 | RAB9A (0.41) | ALDH1A1CNR2HPGDCNR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383615-B2 | Azetidine 2-carboxamide derivatives which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-26 | — | — | US | disclosed |