Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 8/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14724332 | 0.87 | IDO1 (0.47) | HTTSMN1; SMN2ALDH1A1PKMCTSL | |
| SCHEMBL12284781 | 0.85 | IDO1 (0.43) | HTTSMN1; SMN2ALDH1A1PKM | |
| SCHEMBL14982897 | 0.83 | CA9 (0.42) | HTTSMN1; SMN2ALDH1A1PKMGAA | |
| SCHEMBL14985815 | 0.83 | HTT (0.38) | HTTSMN1; SMN2ALDH1A1PKMGAA | |
| SCHEMBL14982890 | 0.81 | SMN1; SMN2 (0.40) | HTTSMN1; SMN2PKM | |
| SCHEMBL12285289 | 0.80 | HTT (0.62) | HTTSMN1; SMN2ALDH1A1PKMCTSL | |
| SCHEMBL14715011 | 0.78 | LMNA (0.47) | SMN1; SMN2ALDH1A1PKMGAA | |
| SCHEMBL12287806 | 0.78 | BTK (0.37) | HTTSMN1; SMN2ALDH1A1PKM | |
| SCHEMBL20908905 | 0.78 | PKM (0.60) | HTTSMN1; SMN2ALDH1A1PKMCTSL | |
| SCHEMBL14724323 | 0.78 | HTT (0.63) | HTTSMN1; SMN2ALDH1A1PKMCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | PEKING UNIVERSITY (CN) | 2013-05-30 | — | — | US | disclosed |
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | PEKING UNIVERSITY (CN) | 2013-05-30 | — | — | US | disclosed |
| EP-2562157-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | Peking University (CN) | 2013-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130136794-A1 | HETEROARYL (ALKYL) DITHIOCARBAMATE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | LTK, ERBB2, ABL1 | HTT 1099/4885SMN1; SMN2 4595/4885ALDH1A1 2942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.