Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 13/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 12/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 12/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17012553 | 0.90 | RXRA (0.49) | CYP1A2ALDH1A1CYP3A4TSHRUSP2 | |
| SCHEMBL14730377 | 0.88 | RXRA (0.45) | CYP1A2ALDH1A1CYP3A4TSHRUSP2 | |
| SCHEMBL17012535 | 0.87 | CYP1A2 (0.54) | CYP1A2ALDH1A1CYP3A4TSHRUSP2 | |
| SCHEMBL13765131 | 0.86 | APP (0.45) | RXRAGRIN1GRIN2B | |
| SCHEMBL13726860 | 0.81 | RXRA (0.53) | RXRAGRIN1GRIN2B | |
| SCHEMBL29366119 | 0.81 | MAOB (0.47) | CYP1A2ALDH1A1CYP3A4TSHRUSP2 | |
| SCHEMBL318524 | 0.81 | MAOB (0.47) | CYP1A2ALDH1A1CYP3A4TSHRUSP2 | |
| SCHEMBL13530488 | 0.80 | RXRA (0.47) | CYP1A2ALDH1A1CYP3A4TSHRUSP2 | |
| SCHEMBL13530312 | 0.80 | ALDH1A1 (0.41) | CYP1A2ALDH1A1CYP3A4TSHRUSP2 | |
| SCHEMBL13529628 | 0.78 | ALDH1A1 (0.40) | CYP1A2ALDH1A1CYP3A4TSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562162-B1 | N-CYANO-4-AMINO-5-FLUORO-PYRIMIDINE DERIVATIVES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2015-08-19 | — | — | EP | disclosed |
| EP-2562163-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |