Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24221429 | 0.88 | EPHX2 (0.44) | CYP3A4MAPTKDM4EIDO1THRB | |
| SCHEMBL11775817 | 0.86 | EPHX2 (0.46) | CYP3A4MAPTKDM4EMEN1KMT2A | |
| SCHEMBL24497367 | 0.83 | CYP3A4 (0.48) | CYP3A4MAPTKDM4EIDO1THRB | |
| SCHEMBL29543866 | 0.80 | SIGMAR1 (0.50) | CYP3A4MAPTIDO1MEN1KMT2A | |
| SCHEMBL28672152 | 0.76 | IDO1 (0.46) | CYP3A4MAPTKDM4EIDO1THRB | |
| SCHEMBL109301 | 0.73 | CYP3A4 (0.52) | CYP3A4MAPTKDM4EIDO1THRB | |
| SCHEMBL11360130 | 0.72 | IDO1 (0.52) | CYP3A4MAPTKDM4EIDO1THRB | |
| SCHEMBL22374228 | 0.72 | PTPN1 (0.38) | CYP3A4MAPTKDM4EIDO1THRB | |
| Hydrochloric Acid SCHEMBL10435079 | 0.71 | MAPT (0.56) | CYP3A4MAPTKDM4EIDO1THRB | |
| SCHEMBL512944 | 0.71 | CYP3A4 (0.45) | CYP3A4MAPTKDM4EIDO1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562163-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |