Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 3/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 5/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13529259 | 0.87 | AURKA (0.40) | AURKAALDH1A1MAPTMAOB | |
| SCHEMBL3168861 | 0.87 | ALDH1A1 (0.40) | AURKAAPPALDH1A1NPC1RAB9A | |
| SCHEMBL13530443 | 0.86 | MAOB (0.45) | AURKASYKFFAR1ALDH1A1MAPT | |
| SCHEMBL13529871 | 0.86 | AURKA (0.46) | AURKASYKAPPFFAR1MAOB | |
| SCHEMBL13529468 | 0.86 | AURKA (0.46) | AURKASYKEGFRJAK3BTK | |
| SCHEMBL13530467 | 0.85 | MAP2K4 (0.47) | AURKASYKEGFRJAK3BTK | |
| SCHEMBL13530502 | 0.84 | KDM4E (0.47) | EGFRJAK3BTKAPPALDH1A1 | |
| SCHEMBL13529604 | 0.84 | CLK1 (0.46) | AURKASYKEGFRJAK3BTK | |
| SCHEMBL13529696 | 0.84 | LMNA (0.44) | ALDH1A1HTTRAB9ASMN1; SMN2 | |
| SCHEMBL13530381 | 0.84 | ALDH1A1 (0.43) | AURKASYKJAK3BTKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562163-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |