Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14715001 | 0.79 | — | — | |
| SCHEMBL14714998 | 0.79 | — | — | |
| SCHEMBL14715246 | 0.69 | — | — | |
| SCHEMBL14715248 | 0.69 | — | — | |
| SCHEMBL14714703 | 0.66 | NPC1 (0.45) | MMP13ALDH1A1 | |
| SCHEMBL21258366 | 0.64 | L3MBTL1 (0.48) | ALDH1A1LMNA | |
| SCHEMBL4580522 | 0.63 | MEN1 (0.64) | HDAC1HDAC3HDAC4HDAC8HDAC6 | |
| SCHEMBL4580523 | 0.63 | MEN1 (0.64) | HDAC1HDAC3HDAC4HDAC8HDAC6 | |
| SCHEMBL21258364 | 0.62 | MEN1 (0.63) | MMP3ALDH1A1 | |
| SCHEMBL6413331 | 0.62 | L3MBTL1 (0.54) | HDAC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562155-A1 | NOVEL HYDROXAMIC ACID DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2013-02-27 | — | — | EP | disclosed |