SCHEMBL21258366

SCHEMBL21258366

CCOC(=O)C(C(=O)NC)N(C)Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.48
▸ MMP8 P22894 2/20 0.48
▸ ALDH1A1 P00352 2/20 0.48
▸ LMNA P02545 2/20 0.48
▸ POLB P06746 2/20 0.48
▸ HSD17B10 Q99714 1/20 0.48
▸ MEN1 O00255 4/20 0.47
▸ KMT2A Q03164 4/20 0.47
▸ NPC1 O15118 3/20 0.46
▸ RAB9A P51151 2/20 0.46
▸ NPY1R P25929 1/20 0.45
▸ NPY2R P49146 1/20 0.45
▸ EPHX2 P34913 1/20 0.43
▸ PPARG P37231 1/20 0.43
▸ TP53 P04637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14714703 0.89 NPC1 (0.45) ALDH1A1HSD17B10MEN1KMT2ANPC1
SCHEMBL14786664 0.88 ALDH1A1 (0.55) L3MBTL1MMP8ALDH1A1LMNAPOLB
SCHEMBL4927817 0.84 ALDH1A1 (0.51) L3MBTL1MMP8ALDH1A1LMNAPOLB
SCHEMBL27475763 0.80 L3MBTL1 (0.60) L3MBTL1MMP8ALDH1A1LMNAPOLB
SCHEMBL11015731 0.78 MEN1 (0.55) L3MBTL1MMP8ALDH1A1LMNAPOLB
SCHEMBL21258291 0.78 MEN1 (0.55) L3MBTL1MMP8ALDH1A1LMNAPOLB
SCHEMBL14202766 0.77 NPC1 (0.51) L3MBTL1ALDH1A1LMNAPOLBHSD17B10
SCHEMBL25205668 0.77 L3MBTL1 (0.52) L3MBTL1MMP8ALDH1A1LMNAPOLB
SCHEMBL26415297 0.77 ALDH1A1 (0.52) L3MBTL1MMP8ALDH1A1LMNAPOLB
SCHEMBL21258364 0.76 MEN1 (0.63) L3MBTL1ALDH1A1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12157717-B2 Compounds for the treatment of bovine or swine respiratory disease INTERVET INC. (US) 2024-12-03 — — US disclosed
US-11498909-B2 Compound acting as antibiotics KBP BIOSCIENCES CO., LTD. (CN) 2022-11-15 — — US disclosed
US-20210347730-A1 COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE INTERVET INC. (US) 2021-11-11 — — US disclosed
US-20210347730-A1 COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE INTERVET INC. (US) 2021-11-11 — — US disclosed
EP-3810571-A1 COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE Intervet International B.V. (NL) 2021-04-28 — — EP disclosed
US-20200392096-A1 COMPOUND ACTING AS ANTIBIOTICS KBP BIOSCIENCES CO., LTD. (CN) 2020-12-17 — — US disclosed
US-20200392096-A1 COMPOUND ACTING AS ANTIBIOTICS KBP BIOSCIENCES CO., LTD. (CN) 2020-12-17 — — US disclosed
EP-3750881-A1 COMPOUND ACTING AS ANTIBIOTICS KBP Biosciences Co., Ltd. (CN) 2020-12-16 — — EP disclosed
EP-3750881-A1 COMPOUND ACTING AS ANTIBIOTICS KBP Biosciences Co., Ltd. (CN) 2020-12-16 — — EP disclosed
WO-2020002238-A1 COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE INTERVET INTERNATIONAL B.V. (NL) 2020-01-02 — — WO disclosed
WO-2019154412-A1 COMPOUND ACTING AS ANTIBIOTICS 山东亨利医药科技有限责任公司 2019-08-15 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210347730-A1 COMPOUNDS FOR THE TREATMENT OF BOVINE OR SWINE RESPIRATORY DISEASE PIGS, BTD, PPARD L3MBTL1 3020/4885MMP8 1172/4885ALDH1A1 845/4885
US-11498909-B2 Compound acting as antibiotics PEPD, NRDC, DPP4 L3MBTL1 2656/4885MMP8 745/4885ALDH1A1 1492/4885
US-20200392096-A1 COMPOUND ACTING AS ANTIBIOTICS PEPD, NRDC, DPP4 L3MBTL1 2656/4885MMP8 745/4885ALDH1A1 1492/4885
US-12157717-B2 Compounds for the treatment of bovine or swine respiratory disease PIGS, BTD, PPARD L3MBTL1 3020/4885MMP8 1172/4885ALDH1A1 845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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