Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 3/20 | 0.49 |
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | MMP8 | P22894 | 3/20 | 0.49 |
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP14 | P50281 | 2/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | MMP16 | P51512 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1221812 | 0.83 | MAPT (0.59) | ALDH1A1MAPTHPGDKDM4EUSP2 | |
| SCHEMBL1221521 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDKDM4EUSP2 | |
| SCHEMBL6384657 | 0.81 | HDAC6 (0.75) | HDAC6HDAC1HDAC8 | |
| SCHEMBL6386623 | 0.80 | HDAC6 (0.77) | HDAC6HDAC1HDAC8 | |
| SCHEMBL17285683 | 0.78 | MAPT (0.71) | ALDH1A1MAPTHPGDKDM4EUSP2 | |
| SCHEMBL2565715 | 0.77 | F2 (0.51) | ALDH1A1HPGDHDAC6HDAC1CTSL | |
| SCHEMBL2565712 | 0.76 | F2 (0.50) | ALDH1A1HPGDHDAC6HDAC1CTSL | |
| SCHEMBL12231007 | 0.74 | TDP1 (0.62) | ALDH1A1MAPTHPGDMMP2 | |
| SCHEMBL2047793 | 0.74 | HPGD (0.63) | ALDH1A1MAPTHPGDKDM4EUSP2 | |
| SCHEMBL12561256 | 0.73 | HDAC1 (0.55) | MAPTHDAC6HDAC1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562155-A1 | NOVEL HYDROXAMIC ACID DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2013-02-27 | — | — | EP | disclosed |