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SCHEMBL14724993

SCHEMBL14724993

CCCOC[C@@H](COC(=O)c1ccccc1)O[C@H]([C@@H](C)OC(=O)c1ccccc1)n1c(=O)sc2cnc(N)nc21

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.33
▸ MEN1 O00255 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ TLR7 Q9NYK1 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ HSD17B10 Q99714 1/20 0.31
▸ PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6984581 0.91 HSD17B10 (0.37) TLR7POLBHSD17B10
SCHEMBL10181868 0.91 HSD17B10 (0.37) TLR7POLBHSD17B10
SCHEMBL10181491 0.75 POLB (0.40) TLR7POLBHSD17B10
SCHEMBL27544332 0.63 LMNA (0.63) LMNAMEN1KMT2A
SCHEMBL9184560 0.61 ALDH1A1 (0.47) MEN1KMT2AHSD17B10PKM
SCHEMBL11077363 0.61 LMNA (0.56) LMNAMEN1KMT2APOLB
SCHEMBL10648907 0.61 ALDH1A1 (0.49) LMNAMEN1KMT2APOLBHSD17B10
SCHEMBL10181949 0.60 ALDH1A1 (0.44) LMNAMEN1KMT2APOLBHSD17B10
SCHEMBL12113431 0.60 ALDH1A1 (0.44) LMNAMEN1KMT2APOLBHSD17B10
SCHEMBL13181899 0.60 MEN1 (0.49) LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2561872-A1 3, 5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo [4,5-d]pyrimidin-2-one compounds and prodrugs thereof Anadys Pharmaceuticals, Inc. (US) 2013-02-27 — — EP disclosed