Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 8/20 | 0.47 |
| ▸ | TUBB | P07437 | 8/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 8/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 8/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 8/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 8/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 8/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 8/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 8/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 8/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 8/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 8/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 8/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 8/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 8/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14725338 | 0.87 | TUBB4A (0.37) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14723506 | 0.80 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14723509 | 0.80 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14721851 | 0.78 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4133065 | 0.75 | TUBB4A (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14723552 | 0.74 | TUBB4A (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14725260 | 0.73 | TUBB4A (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4120173 | 0.73 | TUBB4A (0.45) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1772788 | 0.71 | TUBB4A (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL1772293 | 0.70 | TUBB4A (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026942-A1 | TUBULIN BINDING AGENTS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2013-02-28 | — | — | WO | disclosed |