Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 6/20 | 0.37 |
| ▸ | TUBB | P07437 | 6/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14725262 | 0.87 | TUBB4A (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14725538 | 0.78 | KDM4E (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14725539 | 0.75 | EGFR (0.35) | MAPTKDM4EALDH1A1 | |
| SCHEMBL14725480 | 0.69 | CA1 (0.33) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14723509 | 0.67 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14723506 | 0.67 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14725473 | 0.66 | ALDH1A1 (0.35) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14721851 | 0.66 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14721807 | 0.63 | KDM4E (0.39) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14725265 | 0.62 | GSK3B (0.38) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026942-A1 | TUBULIN BINDING AGENTS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2013-02-28 | — | — | WO | disclosed |