Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722345 | 0.80 | KDM4E (0.35) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL14722455 | 0.79 | TUBB4A (0.44) | — | |
| SCHEMBL14725335 | 0.79 | TUBB4A (0.44) | — | |
| SCHEMBL14725373 | 0.78 | TUBB4A (0.43) | — | |
| SCHEMBL14722633 | 0.78 | TUBB4A (0.43) | — | |
| SCHEMBL14725383 | 0.77 | TUBB4A (0.43) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL14725310 | 0.75 | MAPK10 (0.38) | — | |
| SCHEMBL14721663 | 0.75 | MAPK10 (0.38) | — | |
| SCHEMBL14725359 | 0.74 | HDAC3 (0.32) | — | |
| SCHEMBL14725525 | 0.73 | BTK (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026942-A1 | TUBULIN BINDING AGENTS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2013-02-28 | — | — | WO | disclosed |