Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 7/20 | 0.34 |
| ▸ | PTK6 | Q13882 | 5/20 | 0.34 |
| ▸ | SRC | P12931 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722316 | 0.88 | MEN1 (0.35) | BTKALDH1A1 | |
| SCHEMBL14725529 | 0.84 | MMP1 (0.35) | ABL1PIK3CDEGFRKDRPIK3CA | |
| SCHEMBL14725391 | 0.83 | SMN1; SMN2 (0.35) | BTKABL1PIK3CDEGFRKDR | |
| SCHEMBL14725387 | 0.81 | EPHX2 (0.38) | — | |
| SCHEMBL14725373 | 0.79 | TUBB4A (0.43) | — | |
| SCHEMBL14722633 | 0.79 | TUBB4A (0.43) | — | |
| SCHEMBL14725501 | 0.78 | EPHX2 (0.35) | BACE1 | |
| SCHEMBL14725519 | 0.78 | TUBB4A (0.37) | — | |
| SCHEMBL14725502 | 0.78 | TUBB4A (0.37) | FYNALDH1A1AAK1 | |
| SCHEMBL14722455 | 0.78 | TUBB4A (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026942-A1 | TUBULIN BINDING AGENTS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2013-02-28 | — | — | WO | disclosed |