Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | NAMPT | P43490 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 7/20 | 0.55 |
| ▸ | CA1 | P00915 | 6/20 | 0.55 |
| ▸ | CA12 | O43570 | 5/20 | 0.55 |
| ▸ | CA9 | Q16790 | 4/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | GHSR | Q92847 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14726348 | 0.85 | CA2 (0.72) | NAMPTNPC1CA2CA1CA12 | |
| SCHEMBL14726352 | 0.84 | RAB9A (0.66) | ALDH1A1NAMPTNPC1CA2CA1 | |
| SCHEMBL14726350 | 0.83 | CA2 (0.74) | NAMPTNPC1CA2CA1CA12 | |
| SCHEMBL14726355 | 0.83 | CA2 (0.61) | NAMPTNPC1CA2CA1CA12 | |
| SCHEMBL18960618 | 0.78 | HDAC1 (0.76) | ALDH1A1NAMPTNPC1HDAC1HDAC6 | |
| SCHEMBL14726349 | 0.77 | CA2 (0.62) | NAMPTCA2CA1CA12CA9 | |
| SCHEMBL14726353 | 0.77 | CA1 (0.58) | NAMPTNPC1CA2CA1CA12 | |
| SCHEMBL15956967 | 0.75 | CA1 (0.53) | CA2CA1CA12CA9CA7 | |
| SCHEMBL15574720 | 0.73 | NAMPT (0.64) | ALDH1A1NAMPT | |
| SCHEMBL12348110 | 0.73 | F7 (0.67) | ALDH1A1NAMPTNPC1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053392-A1 | CARBONIC ANHYDRASE INHIBITORS | UNIVERSITETET I OSLO (NO) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053392-A1 | CARBONIC ANHYDRASE INHIBITORS | CA9, CA2, CA4 | ALDH1A1 682/4885NAMPT 729/4885NPC1 2740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.