SCHEMBL14727154

SCHEMBL14727154

Cc1ccc(N(c2ccc(CCOCc3ccccc3)cc2)c2ccc(CCc3ccc(N(c4ccc(CCOCc5ccccc5)cc4)c4ccc(C)c(C)c4)cc3)cc2)cc1C

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
TSHR P16473 1/20 0.37
KCNH2 Q12809 1/20 0.37
S1PR1 P21453 1/20 0.36
BCHE P06276 2/20 0.34
ALDH1A1 P00352 1/20 0.34
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
EBP Q15125 1/20 0.33
TMEM97 Q5BJF2 1/20 0.33
SIGMAR1 Q99720 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14732710 0.92 L3MBTL1 (0.48) L3MBTL1TDP1KCNH2BCHE
SCHEMBL14727184 0.87 TSHR (0.48) L3MBTL1TDP1TSHRKCNH2BCHE
SCHEMBL14727138 0.85 KCNH2 (0.32) KCNH2
SCHEMBL14727157 0.85 KCNH2 (0.32) KCNH2
SCHEMBL14727196 0.84 TSHR (0.54) L3MBTL1TDP1TSHRKCNH2BCHE
SCHEMBL13840020 0.83 KCNH2 (0.32) KCNH2CHRNB4CHRNA3CHRNA7
SCHEMBL3441814 0.80 L3MBTL1 (0.35) L3MBTL1TDP1TSHRKCNH2S1PR1
SCHEMBL15478594 0.80 ALDH1A1 (0.39) TDP1KCNH2ALDH1A1
SCHEMBL11911536 0.79 S1PR1 (0.37) L3MBTL1KCNH2S1PR1ALDH1A1
SCHEMBL14727127 0.79 TSHR (0.47) L3MBTL1TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8663883-B2 Charge-transporting film, photoelectric conversion device, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-04 US disclosed
US-8663883-B2 Charge-transporting film, photoelectric conversion device, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-04 US disclosed
US-20130052570-A1 CHARGE-TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 US disclosed
US-20130052570-A1 CHARGE-TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 US disclosed