SCHEMBL14727239

SCHEMBL14727239

Cc1ccc(N(c2ccc(/C=C/c3ccccc3)cc2)c2ccc(-c3ccc(-c4ccc(N(c5ccc(/C=C/c6ccccc6)cc5)c5ccc(C)cc5C)cc4)cc3)cc2)c(C)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 3/20 0.45
NFE2L2 Q16236 2/20 0.41
CTDSP1 Q9GZU7 1/20 0.40
ALOX5 P09917 2/20 0.39
PTGS1 P23219 2/20 0.39
PTGS2 P35354 2/20 0.39
TTR P02766 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
HPGD P15428 2/20 0.38
NPC1 O15118 1/20 0.37
CYP1A2 P05177 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C19 P33261 1/20 0.37
RAB9A P51151 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.36
INSR P06213 2/20 0.36
APP P05067 2/20 0.35
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14727229 1.00 RELA (0.45) RELANFE2L2CTDSP1ALOX5PTGS1
SCHEMBL15496768 1.00 RELA (0.45) RELANFE2L2CTDSP1ALOX5PTGS1
SCHEMBL14727230 0.95 RELA (0.49) RELANFE2L2CTDSP1ALOX5PTGS1
SCHEMBL18418091 0.95 RELA (0.49) RELANFE2L2CTDSP1ALOX5PTGS1
SCHEMBL17549421 0.94 NFE2L2 (0.40) RELANFE2L2CTDSP1ALOX5PTGS1
SCHEMBL15496775 0.94 NFE2L2 (0.40) RELANFE2L2CTDSP1ALOX5PTGS1
SCHEMBL12680417 0.94 RELA (0.47) RELANFE2L2CTDSP1ALOX5PTGS1
SCHEMBL15496779 0.93 APP (0.39) RELANFE2L2CTDSP1ALOX5PTGS1
SCHEMBL17322718 0.93 APP (0.39) RELANFE2L2CTDSP1ALOX5PTGS1
SCHEMBL15478860 0.93 RELA (0.44) RELANFE2L2CTDSP1ALOX5PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11287756-B2 Positive charging electrophotographic photoreceptor, electrophotographic cartridge and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-29 US disclosed
US-9709906-B2 Charge transport substance, electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-18 US disclosed
US-9709906-B2 Charge transport substance, electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-18 US disclosed
US-20150355559-A1 CHARGE TRANSPORT SUBSTANCE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2015-12-10 US disclosed
US-20150355559-A1 CHARGE TRANSPORT SUBSTANCE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2015-12-10 US disclosed
US-8709689-B2 Electrophotographic photoreceptor, image-forming apparatus, and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2014-04-29 US disclosed
US-8709689-B2 Electrophotographic photoreceptor, image-forming apparatus, and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2014-04-29 US disclosed
US-20140065532-A1 CHARGE TRANSPORT SUBSTANCE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2014-03-06 US disclosed
US-20140065532-A1 CHARGE TRANSPORT SUBSTANCE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2014-03-06 US disclosed
US-20130052574-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2013-02-28 US disclosed
US-20130052574-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150355559-A1 CHARGE TRANSPORT SUBSTANCE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS PDE6C, SLC18A2, SLC1A2 RELA 3900/4885NFE2L2 809/4885CTDSP1 3091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.