SCHEMBL14727249

SCHEMBL14727249

CCCc1ccc(N(c2ccc(/C=C/C=C/c3ccccc3)cc2)c2ccc(/C=C/C=C/c3ccccc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.47
RELA Q04206 2/20 0.46
APP P05067 3/20 0.43
CTDSP1 Q9GZU7 1/20 0.40
LPL P06858 1/20 0.38
LIPG Q9Y5X9 1/20 0.38
ALDH1A1 P00352 2/20 0.37
TRPA1 O75762 1/20 0.37
LMNA P02545 1/20 0.37
ALOX5 P09917 1/20 0.37
MAPK1 P28482 1/20 0.37
CYP24A1 Q07973 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MITF O75030 1/20 0.36
HPGD P15428 1/20 0.36
KLF5 Q13887 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TRPM8 Q7Z2W7 1/20 0.36
CHRM2 P08172 1/20 0.36
HTR1A P08908 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18680230 0.98 MAOB (0.45) MAOBRELAAPPCTDSP1LPL
SCHEMBL18680239 0.94 CNR2 (0.44) MAOBRELAAPPCTDSP1ALDH1A1
SCHEMBL14003991 0.92 RELA (0.52) MAOBRELAAPPCTDSP1LPL
SCHEMBL18680233 0.91 CNR2 (0.44) MAOBRELAAPPCTDSP1ALDH1A1
SCHEMBL10013199 0.90 MAOB (0.44) MAOBRELAAPPALDH1A1TRPA1
SCHEMBL18052489 0.90 MAOB (0.44) MAOBRELAAPPALDH1A1TRPA1
SCHEMBL18680229 0.89 MAOB (0.42) MAOBRELAAPPALDH1A1TRPA1
SCHEMBL18417168 0.89 RELA (0.46) MAOBRELAAPPCTDSP1ALDH1A1
SCHEMBL15759523 0.89 APP (0.43) MAOBRELAAPPALDH1A1TRPA1
SCHEMBL19871000 0.89 CYSLTR2 (0.46) MAOBRELALPLLIPGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11287756-B2 Positive charging electrophotographic photoreceptor, electrophotographic cartridge and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-29 US disclosed
US-9977354-B2 Coating liquid for electrophotographic photoreceptor production, electrophotographic photoreceptor, and image formation apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2018-05-22 US disclosed
US-20170090308-A1 COATING LIQUID FOR ELECTROPHOTOGRAPHIC PHOTORECEPTOR PRODUCTION, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMATION APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2017-03-30 US disclosed
US-20170090308-A1 COATING LIQUID FOR ELECTROPHOTOGRAPHIC PHOTORECEPTOR PRODUCTION, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMATION APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2017-03-30 US disclosed
US-8709689-B2 Electrophotographic photoreceptor, image-forming apparatus, and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2014-04-29 US disclosed
US-8709689-B2 Electrophotographic photoreceptor, image-forming apparatus, and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2014-04-29 US disclosed
US-20130052574-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2013-02-28 US disclosed
US-20130052574-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2013-02-28 US disclosed