Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | LPL | P06858 | 4/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12680109 | 0.98 | KCNH2 (0.48) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL18680259 | 0.98 | KCNH2 (0.48) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL10013199 | 0.95 | MAOB (0.44) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL18052489 | 0.95 | MAOB (0.44) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL18680229 | 0.94 | MAOB (0.42) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL15759523 | 0.94 | APP (0.43) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL18417168 | 0.94 | RELA (0.46) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL18680247 | 0.93 | KCNH2 (0.43) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL18680244 | 0.93 | KCNH2 (0.43) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B | |
| SCHEMBL13108027 | 0.92 | KCNH2 (0.50) | CYSLTR2CYSLTR1TRPA1TRPM2PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180046099-A1 | POLYARYLATE RESIN AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2018-02-15 | — | — | US | disclosed |