SCHEMBL14727355

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14727375	0.92	PDE5A (0.62)	PDE5AABCG2LMNACYP1A2CYP3A4
	SCHEMBL14474988	0.90	PDE5A (0.60)	PDE5ALATS1ABCG2LMNACYP1A2
	SCHEMBL14727347	0.89	PDE5A (0.66)	PDE5AABCG2LMNACYP1A2CYP3A4
	SCHEMBL14474883	0.87	PDE5A (0.64)	PDE5ALATS1ABCG2LMNACYP1A2
	SCHEMBL14475845	0.86	PDE5A (0.60)	PDE5AABCG2LMNACYP1A2CYP3A4
	SCHEMBL14474872	0.85	CYP1A2 (0.72)	PDE5AABCG2LMNACYP1A2CYP3A4
	SCHEMBL14727344	0.85	CYP1A2 (0.73)	PDE5AABCG2LMNACYP1A2CYP3A4
	SCHEMBL20273562	0.85	PDE5A (0.61)	PDE5AABCG2LMNACYP1A2CYP3A4
	SCHEMBL14475442	0.85	ABCG2 (0.63)	PDE5AABCG2LMNACYP1A2CYP3A4
	SCHEMBL14475105	0.84	ABCG2 (0.65)	PDE5AABCG2LMNACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.