SCHEMBL14727595

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16183743	0.89	PDE5A (0.53)	ALDH1A1LMNAGBA1PDE5AUSP1
	SCHEMBL14727824	0.88	PDE5A (0.54)	CYP1A2CYP3A4ALDH1A1LMNAHSD17B10
	SCHEMBL14727599	0.87	PDE5A (0.57)	CYP1A2CYP3A4ALDH1A1LMNAHSD17B10
	SCHEMBL16183747	0.87	CYP1A2 (0.61)	CYP1A2CYP3A4ALDH1A1LMNAHSD17B10
	SCHEMBL16184559	0.85	GBA1 (0.44)	CYP1A2CYP3A4ALDH1A1LMNAHSD17B10
	SCHEMBL14475170	0.85	CYP1A2 (0.59)	CYP1A2CYP3A4ALDH1A1LMNAHSD17B10
	SCHEMBL14727601	0.84	PDE5A (0.55)	CYP1A2CYP3A4ALDH1A1LMNAHSD17B10
	SCHEMBL16183741	0.83	GBA1 (0.59)	CYP1A2CYP3A4ALDH1A1LMNAHSD17B10
	SCHEMBL16183764	0.82	GBA1 (0.51)	ALDH1A1LMNAGBA1PDE5AUSP1
	SCHEMBL14474640	0.82	PDE5A (0.53)	CYP1A2CYP3A4ALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.