SCHEMBL14727671

SCHEMBL14727671

C=C(C)C(=O)CS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.62
RECQL P46063 1/20 0.56
PKM P14618 3/20 0.53
POLB P06746 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HSD11B1 P28845 1/20 0.51
MAPT P10636 1/20 0.51
HSD17B10 Q99714 1/20 0.51
CYP3A4 P08684 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
LMNA P02545 1/20 0.50
KMT2A Q03164 3/20 0.49
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA9 Q16790 2/20 0.49
MEN1 O00255 1/20 0.49
PAX8 Q06710 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28268848 0.85 ALDH1A1 (0.61) ALDH1A1RECQLPKMPOLBSMN1; SMN2
SCHEMBL21861838 0.84 ALDH1A1 (0.61) ALDH1A1RECQLPKMPOLBSMN1; SMN2
SCHEMBL7925265 0.82 ALDH1A1 (0.63) ALDH1A1RECQLPKMHSD11B1MAPT
SCHEMBL455924 0.82 ALDH1A1 (0.69) ALDH1A1RECQLPKMPOLBSMN1; SMN2
SCHEMBL1694716 0.80 ALDH1A1 (0.66) ALDH1A1RECQLPKMPOLBSMN1; SMN2
SCHEMBL8572063 0.80 ALDH1A1 (0.61) ALDH1A1RECQLPKMPOLBHSD11B1
Acetic Acid SCHEMBL8984837 0.79 ALDH1A1 (0.65) ALDH1A1RECQLPKMHSD11B1MAPT
SCHEMBL28141711 0.79 ALDH1A1 (0.65) ALDH1A1RECQLPKMHSD11B1MAPT
SCHEMBL7743433 0.79 ALDH1A1 (0.69) ALDH1A1RECQLPKMHSD11B1MAPT
SCHEMBL924405 0.79 ALDH1A1 (0.69) ALDH1A1RECQLPKMHSD11B1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9046774-B2 Positive-working lithographic printing plate precursor for infrared laser and process for making lithographic printing plate FUJIFILM CORPORATION (JP) 2015-06-02 US disclosed
US-9040219-B2 Image forming material, planographic printing plate precursor, and method for manufacturing a planographic printing plate FUJIFILM CORPORATION (JP) 2015-05-26 US disclosed
US-8840807-B2 Polymerizable compound JNC CORPORATION (JP) 2014-09-23 US disclosed
US-20140065538-A1 POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR FOR INFRARED LASER AND PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2014-03-06 US disclosed
US-8632951-B2 Positive-working lithographic printing plate precursor for infrared laser and process for making lithographic printing plate FUJIFILM CORPORATION (JP) 2014-01-21 US disclosed
US-20130048912-A1 POLYMERIZABLE COMPOUND JNC PETROCHEMICAL CORPORATION (JP) 2013-02-28 US disclosed
US-20120052445-A1 IMAGE FORMING MATERIAL, PLANOGRAPHIC PRINTING PLATE PRECURSOR, AND METHOD FOR MANUFACTURING A PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2012-03-01 US disclosed
US-20110217656-A1 POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR FOR INFRARED LASER AND PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048912-A1 POLYMERIZABLE COMPOUND PYM1, ZYX, CPNE4 ALDH1A1 2498/4885RECQL 2831/4885PKM 1267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.