SCHEMBL455924

SCHEMBL455924

CC(=O)CS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.69
POLB P06746 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
RECQL P46063 1/20 0.61
PKM P14618 3/20 0.57
HSD11B1 P28845 1/20 0.56
MAPT P10636 1/20 0.56
HSD17B10 Q99714 1/20 0.56
CYP3A4 P08684 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
LMNA P02545 1/20 0.54
KMT2A Q03164 3/20 0.53
MEN1 O00255 1/20 0.53
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA9 Q16790 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL7492225 0.88 ALDH1A1 (0.56) ALDH1A1POLBSMN1; SMN2RECQLPKM
SCHEMBL1694716 0.85 ALDH1A1 (0.66) ALDH1A1POLBSMN1; SMN2RECQLPKM
Acetic Acid SCHEMBL8984837 0.84 ALDH1A1 (0.65) ALDH1A1RECQLPKMHSD11B1MAPT
SCHEMBL7385583 0.83 ALDH1A1 (0.67) ALDH1A1POLBSMN1; SMN2RECQLHSD11B1
SCHEMBL924405 0.83 ALDH1A1 (0.69) ALDH1A1RECQLPKMHSD11B1MAPT
SCHEMBL14727671 0.82 ALDH1A1 (0.62) ALDH1A1POLBSMN1; SMN2RECQLPKM
SCHEMBL2027971 0.82 NPC1 (0.67) ALDH1A1POLBSMN1; SMN2HSD11B1MAPT
SCHEMBL10338418 0.82 ALDH1A1 (0.67) ALDH1A1RECQLPKMHSD11B1MAPT
SCHEMBL608774 0.82 ALDH1A1 (1.00) ALDH1A1RECQLPKMHSD11B1MAPT
SCHEMBL8447060 0.82 ALDH1A1 (0.67) ALDH1A1SMN1; SMN2RECQLPKMHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115286559-B Preparation method of key intermediate of anti-new crown drug Pa Luo Weide 上海再启生物技术有限公司 2023-11-17 CN claimed
CN-115286559-A Preparation method of anti-new crown drug Parovirid key intermediate 上海再启生物技术有限公司 2022-11-04 CN claimed
CN-113334523-B PB plate odor control process 河南佳诺威木业有限公司 2022-06-07 CN claimed
CN-114058063-A Preparation process of rubber-plastic heat-insulating material 合肥汇东橡塑有限公司 2022-02-18 CN claimed
CN-113334523-A PB plate odor control process 河南佳诺威木业有限公司 2021-09-03 CN claimed
CN-110698712-A Preparation method of XPE foaming agent 浙江杰上杰新材料有限公司 2020-01-17 CN claimed
CN-110684486-A Low-temperature automobile expansion adhesive and preparation method thereof 浙江杰上杰新材料有限公司 2020-01-14 CN claimed
CN-109517372-A A kind of matt nylon film and preparation method thereof 湖南工业大学 2019-03-26 CN claimed
EP-1758833-B1 IMPROVING THE FREEZE-THAW DURABILITY OF DRY CAST CEMENTITIOUS MIXTURES CONSTR RES & TECH GMBH (DE) 2016-06-01 EP claimed
EP-2822912-A1 USE OF AT LEAST ONE SUPERABSORBENT POLYMER (PSA) (B), IN A DRY COMPOSITION BASED ON A MINERAL BINDER AND USED FOR PREPARING A HARDENABLE MOIST FORMULATION FOR THE BUILDING INDUSTRY PAREXGROUP SA (FR) 2015-01-14 EP claimed
EP-1758836-A2 PROVIDING FREEZING AND THAWING RESISTANCE TO CEMENTITIOUS COMPOSITIONS DIE Construction Research & Technology GmbH (DE) 2007-03-07 EP claimed
WO-2006133855-A2 METHOD OF DELIVERY OF AGENTS PROVIDING FREEZING AND THAWING RESISTANCE TO CEMENTITIOUS COMPOSITIONS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2006-12-21 WO claimed
US-20060281835-A1 Method of delivery of agents providing freezing and thawing resistance to cementitious compositions CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2006-12-14 US claimed
WO-2005123624-A2 PROVIDING FREEZING AND THAWING RESISTANCE TO CEMENTITIOUS COMPOSITIONS CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2005-12-29 WO claimed
WO-2005123619-A2 IMPROVING THE FREEZE-THAW DURABILITY OF DRY CAST CEMENTITIOUS MIXTURES CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2005-12-29 WO claimed
US-20050274294-A1 Freeze-thaw durability of dry cast cementitious mixtures CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2005-12-15 US claimed
US-20050274285-A1 Providing freezing and thawing resistance to cementitious compositions CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2005-12-15 US claimed
US-20030178927-A1 Cathode for electron tube and method for manufacturing the same SAMSUNG SDI CO., LTD. A CORPORATION ORGANIZED UNDER THE LAWS OF THE REPUBLIC OF KOREA (KR) 2003-09-25 US claimed
CN-1045802-A A kind of cross-linking foamed polybutadiene rubber composite CHINA YANSHAN UNION FOREIGN TR (CN) 1990-10-03 CN claimed
CN-1045801-A But a kind of polybutadiene rubber composite of sulfur foam CHINA YANSHAN UNION FOREIGN TR (CN) 1990-10-03 CN claimed