SCHEMBL14727684

SCHEMBL14727684

C=C(C)C(=O)Oc1ccc(C2(c3ccc(OC(=O)C(=C)C)cc3)CCC(CCC3CCC(CCCCC)CC3)CC2)cc1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.38
ATM Q13315 1/20 0.38
ELANE P08246 1/20 0.37
GPR119 Q8TDV5 7/20 0.36
ADORA3 P0DMS8 1/20 0.35
MEN1 O00255 1/20 0.34
LSS P48449 2/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14727675 0.98 KMT2A (0.39) KMT2AATMELANEGPR119ADORA3
SCHEMBL14727703 0.96 GPR119 (0.36) KMT2AATMELANEGPR119ADORA3
SCHEMBL14727698 0.95 THRB (0.35) KMT2AATMELANEGPR119ADORA3
SCHEMBL14727705 0.94 ELANE (0.38) KMT2AELANEGPR119MEN1HPGD
SCHEMBL14727683 0.94 THRB (0.44) KMT2AATMELANEGPR119ADORA3
SCHEMBL14478762 0.94 KMT2A (0.36) KMT2AATMELANEGPR119ADORA3
SCHEMBL14727682 0.93 KMT2A (0.36) KMT2AATMELANEGPR119ADORA3
SCHEMBL14727681 0.92 KMT2A (0.40) KMT2AATMELANEGPR119ADORA3
SCHEMBL21074588 0.89 LSS (0.34) KMT2AGPR119ADORA3MEN1LSS
SCHEMBL14727697 0.89 THRB (0.34) KMT2AATMELANEGPR119ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8840807-B2 Polymerizable compound JNC CORPORATION (JP) 2014-09-23 US disclosed
US-20130048912-A1 POLYMERIZABLE COMPOUND JNC PETROCHEMICAL CORPORATION (JP) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048912-A1 POLYMERIZABLE COMPOUND PYM1, ZYX, CPNE4 KMT2A 617/4885ATM 2670/4885ELANE 2834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.