Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.34 |
| ▸ | KLK1 | P06870 | 3/20 | 0.34 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | HPN | P05981 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14727694 | 0.84 | THRB (0.50) | THRBADORA3NFKB1NFKB2RELA | |
| SCHEMBL14727719 | 0.80 | NPC1 (0.43) | THRBPRSS1NFKB1NFKB2RELA | |
| SCHEMBL14727678 | 0.78 | THRB (0.42) | THRBADORA3NFKB1NFKB2RELA | |
| SCHEMBL14173044 | 0.77 | THRB (0.49) | THRBADORA3KMT2AMAPTMEN1 | |
| SCHEMBL14727674 | 0.75 | THRB (0.50) | THRBADORA3KMT2AMEN1 | |
| SCHEMBL14192345 | 0.74 | THRB (0.62) | THRBPRSS1KLK1TMPRSS2KMT2A | |
| SCHEMBL17364494 | 0.74 | KMT2A (0.52) | PRSS1KLK1TMPRSS2KMT2AMAPT | |
| SCHEMBL15397339 | 0.74 | THRB (0.64) | THRBPRSS1KLK1TMPRSS2TP53 | |
| SCHEMBL14727676 | 0.73 | THRB (0.51) | THRBADORA3KMT2AMEN1 | |
| SCHEMBL14173043 | 0.73 | THRB (0.44) | THRBADORA3NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8840807-B2 | Polymerizable compound | JNC CORPORATION (JP) | 2014-09-23 | — | — | US | disclosed |
| US-20130048912-A1 | POLYMERIZABLE COMPOUND | JNC PETROCHEMICAL CORPORATION (JP) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130048912-A1 | POLYMERIZABLE COMPOUND | PYM1, ZYX, CPNE4 | THRB 4473/4885PRSS1 2141/4885KLK1 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.