Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | TET3 | O43151 | 4/20 | 0.34 |
| ▸ | FBXL19 | Q6PCT2 | 4/20 | 0.34 |
| ▸ | TET1 | Q8NFU7 | 4/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.34 |
| ▸ | CXXC4 | Q9H2H0 | 4/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.34 |
| ▸ | CXXC5 | Q7LFL8 | 3/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14727678 | 0.86 | THRB (0.42) | THRBELANENFKB1NFKB2RELA | |
| SCHEMBL14173044 | 0.85 | THRB (0.49) | THRBADORA3KMT2ATET3FBXL19 | |
| SCHEMBL14727700 | 0.84 | THRB (0.42) | THRBNFKB1NFKB2RELAADORA3 | |
| SCHEMBL14727674 | 0.83 | THRB (0.50) | THRBADORA3KMT2ATET3FBXL19 | |
| SCHEMBL14727701 | 0.81 | THRB (0.40) | THRBKMT2ASMN1; SMN2 | |
| SCHEMBL14727676 | 0.81 | THRB (0.51) | THRBADORA3KMT2ATHRA | |
| SCHEMBL14727699 | 0.81 | THRB (0.40) | THRBKMT2ASMN1; SMN2 | |
| SCHEMBL14173043 | 0.80 | THRB (0.44) | THRBNFKB1NFKB2RELAADORA3 | |
| SCHEMBL14727720 | 0.80 | THRB (0.52) | THRBADORA3KMT2ATET3FBXL19 | |
| SCHEMBL7561728 | 0.78 | THRB (0.72) | THRBNFKB1NFKB2RELAADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8840807-B2 | Polymerizable compound | JNC CORPORATION (JP) | 2014-09-23 | — | — | US | disclosed |
| US-8840807-B2 | Polymerizable compound | JNC CORPORATION (JP) | 2014-09-23 | — | — | US | disclosed |
| US-20130048912-A1 | POLYMERIZABLE COMPOUND | JNC PETROCHEMICAL CORPORATION (JP) | 2013-02-28 | — | — | US | disclosed |
| US-20130048912-A1 | POLYMERIZABLE COMPOUND | JNC PETROCHEMICAL CORPORATION (JP) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130048912-A1 | POLYMERIZABLE COMPOUND | PYM1, ZYX, CPNE4 | THRB 4473/4885ELANE 2834/4885NFKB1 3040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.